SeraSeal Global Hemorrhage Preparedness Index
A clinical and infrastructure needs assessment across 180 nations
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Bleeding is the world's most preventable cause of surgical death.
Hemorrhage kills more people on the operating table, on the battlefield, and at the scene of trauma than almost any other single factor. It kills fast. It kills people who should survive. And in a world of sophisticated medicine, the tools available to stop it have not fundamentally changed in generations.
Cauterization destroys tissue with a third-degree burn. It cannot reach hidden bleeds. It cannot be used on the organs most likely to hemorrhage. Fibrin glues require mixing, preparation, and a dry surface. Direct pressure depends on time the surgeon does not always have, and on a coagulation system that may already be failing.
For the one in four surgical patients presenting with coagulopathy, for every patient maintained on anticoagulant therapy, for every premature infant with underdeveloped clotting capacity -- the conventional tools fall short. These patients deserve a solution that does not depend on a functioning coagulation system.
SeraSeal was designed for all of them.
Tomorrow's Technology Today.
SeraSeal is a one-component topical hemostatic agent that stops all forms of bleeding on contact -- venous, arterial, and bone marrow -- in seconds, without pressure, without tissue destruction, and without interrupting a patient's anticoagulant therapy.
It is the only hemostatic agent classified as primary. Every other agent on the market is an adjunct -- a secondary tool that assists bleeding control under limited conditions. SeraSeal is the first agent designed to be the primary intervention, effective across the full spectrum of hemorrhage including the most severe classes of blood loss.
Applied topically to the bleeding site, SeraSeal catalyzes the body's own coagulation cascade, forming a dual barrier of platelet seal and fibrin clot in seconds. It requires no mixing, no preparation, and no dry surface. Once hemostasis has occurred, it is removed cleanly by irrigation within two minutes, leaving no residue and no tissue damage.
It works in the operating room, at the trauma scene, through an endoscope, across a bone surface, and in the hands of a first responder in the field.
Where SeraSeal belongs.
Every surgical specialty confronts bleeding. SeraSeal has been applied across a broad range of surgical disciplines and tissues, in patients of all ages including newborns. It reduces mean blood loss by more than 60% compared to cauterization, shortens surgical time, reduces transfusion requirements, and preserves tissue that cauterization would destroy.
(Wortham L., Acta Scientific Gastrointestinal Disorders, 2025)
Ninety percent of potentially survivable battlefield deaths involve hemorrhage. Eighty-six percent of all battlefield deaths occur within the first thirty minutes of wounding, long before a surgeon is available. SeraSeal's foam canister format brings primary hemostatic capability to medics, paramedics, and first responders who need something that works on any bleed type, immediately, with no preparation and no surgical training required.
Nine out of ten people in low and middle-income countries lack access to safe, timely surgical care. Where blood banks are under-resourced and surgical infrastructure is thin, every unit of blood saved and every minute cut from surgical time has an impact that goes far beyond the operating room. SeraSeal has been deployed worldwide precisely because bleeding does not observe the boundaries of healthcare infrastructure.
Built on Science. Driven by Mission.
Wortham Laboratories is a privately held biotech company headquartered in Chattanooga, Tennessee. Our research has been focused on a single conviction: that the most important contribution we can make to medicine is a product proven to save lives.
SeraSeal is the result of that conviction -- more than one million successful procedures and a safety record with zero reported adverse events across a broad range of tissues and surgical disciplines.